1x48 - Digimon: Digital Monsters

Kari falls ill, and Tai becomes nearly hysterical as he and Izzy search for medicine. However, the DigiDestined learn too late that the city they are in is under Machinedramon's control. Although they dismantle the tracking system, Tai and Izzy return and are nearly killed by a Megadramon and Gigadramon, but Angemon saves them. Unfortunately Machinedramon fires at the building the kids are in, sending them into the sewers below.