5x22 - Dragon Ball Z Kai

As Vegeta is ensnared by Buu, Trunks and Goten can no longer stand by, and rush to the scene to rescue him, while Piccolo attacks the defenseless Babidi and rips him to pieces. Feeling he cannot defeat Buu with conventional means, Vegeta says his farewells to Trunks before knocking both children out, instructing Piccolo to take them far away. Once everyone is cleared from the scene, Vegeta uses his last resort, overloading his Super Saiyan form and sacrificing himself in a massive self-destructive explosion, in order to obliterate Buu.