The Big One is a 1992 British comedy-drama television series starring Sandi Toksvig as Deddie Tolbert and Mike McShane as James Howard.
Seven episodes were broadcast on Channel 4 from 5 March to 16 April 1992. The series was written by Elly Brewer and Toksvig, and directed by John Henderson. Guest actors included Mel Martin, Jim Sweeney and Dexter Fletcher.
The show is referenced negatively in Bottom Live by Ade Edmondson.