Two FBI agents, one male and one female, are partnered together and sent to unusual parts of the country to work with local police and solve crimes. Their cases expose them to different cultures each week (i.e. one week an Aryan nation community, the next an upper class neighborhood in Boston). One is a former high school teacher who is driven by passion and impulse, while the other is more centered and logical. Initially, the two are reluctant partners, though they gradually develop a strong, platonic bond, learning to trust and depend on each other.